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ORIGINAL ARTICLE
Year : 2020  |  Volume : 7  |  Issue : 1  |  Page : 24-27

Tranexamic acid reduces blood loss and need of blood transfusion in hemiarthroplasty: An observational study


1 Department of Orthopedics, SUT Academy of Medical Science (SUTAMS), Trivandrum, Kerala, India
2 Department of Pharmacology, SUT Academy of Medical Science (SUTAMS), Trivandrum, Kerala, India
3 Department of Community Medicine, SUT Academy of Medical Science (SUTAMS), Trivandrum, Kerala, India

Correspondence Address:
Dr. Sangeetha Gopinath
Department of Pharmacology, SUT Academy of Medical Science (SUTAMS), Vencode P.O. Vattappara, Trivandrum, Kerala.
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jhrr.JHRR_10_20

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Aim: The aim of this study was to evaluate the effects of tranexamic acid on postoperative bleeding and transfusion requirement. Materials and Methods: A total of 70 patients who underwent hemiarthroplasty between January 2015 and December 2016 were retrospectively analyzed using patient case files, discharge database, and blood bank database. The blood transfusion requirement, preoperative and postoperative hemoglobin levels, and drain volume were noted. Pearson chi-square test and independent t test were applied to analyze the data. Results: The blood transfusion requirements were significantly lower in those who received tranexamic acid (17.5% vs. 66.67%; P < 0.001). Patients who had received tranexamic acid had significantly less drop in postoperative hemoglobin (0.99 ± 0.32 vs. 2.46 ± 0.52; P < 0.001) and drain volume (102.50 ± 29.62 vs. 274.67 ± 70.01; P < 0.001). Conclusion: In patients who underwent hemiarthroplasty, tranexamic acid reduced the blood loss and the transfusion requirement.


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