• Users Online: 152
  • Home
  • Print this page
  • Email this page
Home Current issue Ahead of print Search About us Editorial board Archives Submit article Author Guidelines Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2016  |  Volume : 3  |  Issue : 1  |  Page : 28-30

Study of dyslipidemia and antioxidant status in chronic kidney disease patients at a hospital in South East Asia


1 Department of Biochemistry, Sri Aurobindo Institute of Medical Sciences, Indore, Madhya Pradesh, India
2 Department of Biochemistry, Saraswati Institute of Medical Sciences, Hapur, Uttar Pradesh, India
3 Department of Anatomy, MIMS, Bhopal, Madhya Pradesh, India
4 Department of Pharmacology, IMS and SUM Hospital, SOA University, Bhubaneswar, Odisha, India

Correspondence Address:
Kamal Kachhawa
Department of Biochemistry, Sri Aurobindo Institute of Medical Sciences, Indore, Madhya Pradesh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2394-2010.177494

Rights and Permissions

Introduction: The prevalence of hyperlipidemia is a most common problem in developed and developing society. Abnormal increase level of total cholesterol, triglyceride (TG), very low-density lipoprotein (VLDL), and LDL caused cardiovascular disease (CVD) in chronic kidney disease (CKD). Dyslipidemia is a known marker for CVD in the common population. Significant abnormal total cholesterol, LDL, TG, VLDL, and high-density lipoprotein (HDL) are present in CKD patients. Materials and Methods: In this study, we tried to find out the levels of lipid profile and antioxidant levels in CKD patients and its correlation with CVD. This study included 159 human subjects of age group between 40 and 65 years, out of which 78 patients were CKD and rest 81 patients are matched healthy subjects (control group). Results and Discussion: Our study showed a significant increase in Blood Pressure compared to control subjects. Lipid profile (total cholesterol, VLDL, TG, and LDL) was found significantly deranged (P < 0.001) and there was a decrease in the levels of HDL-cholesterol compared to control subjects. Conclusion: Enzyme level (superoxide dismutase) was significantly decreased, and malondialdehyde level was significantly increased compared to control subjects which show the effect of dyslipidemia and oxidative stress associated with the chronic kidney disorder.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2035    
    Printed53    
    Emailed12    
    PDF Downloaded212    
    Comments [Add]    
    Cited by others 1    

Recommend this journal